Dexpanthenol belongs to a derivative of pantothenic acid (vitamin B5). It can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. The later one is extremely hygroscopic and binds water effectively. Therefore, Dexpanthenol can be used as a moisturizer. It is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. In ointments, it can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. It is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. The exact mechanism of action of Dexpanthenol is still unclear, perhaps through its enhancing effect on acetylcholine.
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The CAS number of Dexpanthenol is 81-13-0.
More information of Dexpanthenol 81-13-0 are:
CAS Number |
81-13-0 |
Density |
1.166 g/cm3 |
Melting Point |
64~69℃ |
Boiling Point |
483.6 °C at 760 mmHg |
Flash Point |
246.3 °C |
Vapor Pressure |
2.21E-11mmHg at 25°C |
Refractive Index |
1.495-1.502 |
HS CODE |
29241990 |
PSA |
89.79000 |
LogP |
-0.74470 |
Pka |
13.03±0.20(Predicted) |
The chemical formula of Dexpanthenol is C9H19NO4 which containing 9 Carbon atoms,19 Hydrogen atoms,1 Nitrogen atoms and 4 Oxygen atoms,and the molecular weight, and the molecular weight of Dexpanthenol is 205.254
Dexpanthenol belongs to a derivative of pantothenic acid (vitamin B5). It can penetrate the skin and mucous membrane to be quickly oxidized to pantothenic acid. The later one is extremely hygroscopic and binds water effectively. Therefore, Dexpanthenol can be used as a moisturizer. It is added to pharmaceutical and cosmetic products to relieve itching and improve wound healing. In ointments, it can be used for the treatment of sunburns, mild burns, minor skin injuries and disorders. It is also immediately applied after major abdominal surgery to minimize the possibility of paralytic ileus. In addition, it can also be supplemented into the commercial shampoos and hair conditioners to lubricate the hair shaft and give the hair a shiny appearance. The exact mechanism of action of Dexpanthenol is still unclear, perhaps through its enhancing effect on acetylcholine.
InChI:InChI=1/C9H19NO4/c1-9(2,6-12)7(13)8(14)10-4-3-5-11/h7,11-13H,3-6H2,1-2H3,(H,10,14)/t7-/m1/s1
Relevant articles related to Dexpanthenol:
Article |
Source |
Determination of panthenol enantiomers in cosmetic preparations using an achiral-chiral–coupled column HPLC system |
Hroboňová, Katarína,Lomenova, Anna , p. 191 - 199 (2019/12/15) |
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